【文献解读】UTMD技术进行药物或基因递送
摘要
微泡形式的超声造影剂作为一种分子显像剂在灌注监测中越来越受欢迎。微泡由生物相容性材料制成，可以经静脉注射使用，有些已被批准用于临床。在一定能量的超声辐照下，微泡可以被击破，这种爆破现象可以应用于靶向给药和增强药物作用。由于超声场可以聚焦于目标组织和器官，利用微泡给药可以提高治疗的选择性，减少不良的药物副作用。值得注意的是，微泡还能够增强超声能量在组织中的沉积，并作为空化核增加细胞内药物的递送。
参考文献
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